Aloeride Has Anti-Diabetic Potential

Plants have been used as a source of medicine through out the years of time. The use of plants in treatment of various human ailments has been noted in many of the ancient Indian literature. There are about 45,000 plant species in India and several thousands have been used as medicine because of the purported medicinal properties. In the last few decades the studies performed on the plants mentioned in the literature or were used traditionally for diabetes have shown to actually have anti-diabetic properties. The study reviews 45 of the anti-diabetic plants and their products have shown experimental or clinical anti-diabetic activity. The most commonly studied and the most successful of these plants used in association of diabetes and their problems are the Allium cepa, Allium sativum, Aloe vera, Cajanus cajan, Coccinia indica, Caesalpinia bonducella, Ficus bengalenesis, Gymnema sylvestre, Momordica charantia, Ocimum sanctum, Pterocarpus marsupium, Swertia chirayita, Syzigium cumini, Tinospora cordifolia and Trigonella foenum graecum. A varying degree of hypoglycemia and anti-hyperglycemic activity were shown in a variety of degrees in all of the plants.

In preliminary clinical and experimental observations, the dried sap of the al0e plant is a traditional remedy used for diabetes in the Arabian Peninsula. In fact it is one of the many traditional remedies used in diabetes in the Arabian Peninsula. 5 patients wit non-insulin-dependent diabetes and in Swiss albino mice were studied. With one half teaspoon of the aloes ingested daily for 4-14 weeks, the fasting serum glucose level fell in every patient from 273 to 151 with no weight gain or loss. In normal mice, the doses of 10 mg twice daily of glibenclamide and 500 mg twice daily of aloes induce hypoglycaemia (an abnormally low level of sugar) after 5 days. 71 from 91, versus 130 in the control animals only glibenclamide was effective after 3 days. Glibenclamide and aloes noticeably reduced the fasting plasma glucose in the diabetic mice after 3 days. Only the aloes was useful after that and by day number 7, the plasma glucose was 394 versus 64, in the controls and 726 in the glibenclamide treated group. The conclusion to this study was aloes contains a hypoglycaemic agent, which lowers the blood glucose, however the specific cause is unknown.

In this study the objective is to perform a methodical review of the published literature on the effectiveness and the safety of the use of herbal supplements, vitamins and minerals, and therapies as glucose control in patients with diabetes.

An electronic literary search was perform of Medline, Oldmedline, Cochrane Library Database, and performed hand searches and consulting with experts in the field. This study also included any available clinical studies involving human participants and examined glycemic control. When data had been extracted in a consistent manner, two independent investigators assessed the procedural quality of the randomized controlled trials using the Jadad scale.

The Results found a total of 108 trials examining 35 herbs, whether single or in combination, and 9 vitamin/mineral supplements, which involved 4,565 patients with diabetes or weakened glucose tolerance. The criteria was met and analyzed. There were 58 controlled clinical trials, 42 were randomized and 16 were non-randomized trials, which mostly used patients with type 2 diabetes. Of the 58 trials, the direction of the evidence form improved glucose control was positive in 76%, which equals to 44 of the 58. Very few adverse effects were reported.

The Conclusion is still insufficient evidence to draw definitive conclusions about the effectiveness of individual herbs, however they do appear to be safe. With the data available it does suggest several of the herbal supplements need further study because of their positive results in the preliminary trials. These are Aloe vera, vanadium, nopal and a few others.

With Aloeride containing pure Aloe vera it is safe to say, the findings show positive results in lowering glucose among type II diabetics, and it has been found to be safe to take. Check into the other qualities of Aloeride with pure Aloe Vera. You just might be surprised.